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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK1IP1
All Species:
19.39
Human Site:
S345
Identified Species:
32.82
UniProt:
Q9NWT1
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NWT1
NP_060376.2
392
43964
S345
V
H
K
E
E
K
R
S
K
P
N
T
K
K
R
Chimpanzee
Pan troglodytes
XP_518863
393
44017
S346
V
H
K
E
E
K
Q
S
K
P
N
T
K
K
R
Rhesus Macaque
Macaca mulatta
XP_001087458
392
43967
S345
V
Y
K
E
E
K
Q
S
K
P
N
T
K
K
R
Dog
Lupus familis
XP_535884
391
43743
S347
V
Q
E
E
E
R
Q
S
K
S
N
A
K
K
C
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCE5
382
42097
S340
D
T
V
Q
E
E
T
S
E
P
N
S
E
K
S
Rat
Rattus norvegicus
NP_001032433
382
42216
S340
D
K
I
Q
E
E
A
S
A
P
N
A
E
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514604
358
39493
P317
S
N
K
N
L
G
H
P
V
E
N
V
G
R
E
Chicken
Gallus gallus
Q5ZKU8
369
41214
K328
K
P
S
A
V
K
K
K
K
V
C
G
M
N
K
Frog
Xenopus laevis
Q68FJ6
363
40513
K322
A
V
T
A
S
A
V
K
D
C
D
R
P
K
K
Zebra Danio
Brachydanio rerio
Q6TNS2
368
40882
D327
A
Q
A
T
T
S
E
D
V
L
D
P
L
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001181466
538
58474
I452
Q
D
G
R
N
V
F
I
T
G
L
L
V
A
A
Poplar Tree
Populus trichocarpa
XP_002318775
332
35851
M291
V
W
D
V
R
M
S
M
K
E
K
P
N
P
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_176683
345
37437
L304
A
K
E
N
T
K
P
L
A
E
T
N
T
K
S
Baker's Yeast
Sacchar. cerevisiae
P20484
468
53654
T423
M
K
K
R
D
A
E
T
A
D
I
G
D
Q
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
96.1
85.4
N.A.
72.4
75.2
N.A.
65
63
60.4
53
N.A.
N.A.
N.A.
N.A.
27.7
Protein Similarity:
100
99.7
97.6
92.8
N.A.
83.9
83.4
N.A.
76.5
78.5
75
69.6
N.A.
N.A.
N.A.
N.A.
44.8
P-Site Identity:
100
93.3
86.6
53.3
N.A.
33.3
33.3
N.A.
13.3
13.3
6.6
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
73.3
N.A.
66.6
53.3
N.A.
26.6
26.6
20
6.6
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
26.2
N.A.
N.A.
27
20.9
N.A.
Protein Similarity:
46.1
N.A.
N.A.
47.9
37.8
N.A.
P-Site Identity:
13.3
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
0
8
15
0
15
8
0
22
0
0
15
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
8
% C
% Asp:
15
8
8
0
8
0
0
8
8
8
15
0
8
0
0
% D
% Glu:
0
0
15
29
43
15
15
0
8
22
0
0
15
0
8
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
8
0
0
0
8
0
15
8
0
0
% G
% His:
0
15
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
8
0
0
8
0
0
0
0
% I
% Lys:
8
22
36
0
0
36
8
15
43
0
8
0
29
58
15
% K
% Leu:
0
0
0
0
8
0
0
8
0
8
8
8
8
0
8
% L
% Met:
8
0
0
0
0
8
0
8
0
0
0
0
8
0
0
% M
% Asn:
0
8
0
15
8
0
0
0
0
0
50
8
8
8
0
% N
% Pro:
0
8
0
0
0
0
8
8
0
36
0
15
8
8
8
% P
% Gln:
8
15
0
15
0
0
22
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
15
8
8
8
0
0
0
0
8
0
8
22
% R
% Ser:
8
0
8
0
8
8
8
43
0
8
0
8
0
0
29
% S
% Thr:
0
8
8
8
15
0
8
8
8
0
8
22
8
0
0
% T
% Val:
36
8
8
8
8
8
8
0
15
8
0
8
8
8
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _